Detalhe da pesquisa
1.
Discovery of a structural class of antibiotics with explainable deep learning.
Nature
; 626(7997): 177-185, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38123686
2.
Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.
Nature
; 609(7926): 408-415, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35831509
3.
Correction to "An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections".
ACS Cent Sci
; 8(9): 1362, 2022 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36188352
4.
An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections.
ACS Cent Sci
; 8(8): 1145-1158, 2022 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36032774
5.
Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.
Cell Chem Biol
; 26(6): 781-791.e6, 2019 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30930162
6.
MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.
Cell Chem Biol
; 23(12): 1458-1467, 2016 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27939900
7.
Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis.
PLoS One
; 11(8): e0161740, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27580226
8.
Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens.
ACS Med Chem Lett
; 7(7): 692-6, 2016 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27437079